The world's fastest manned (rocket) airplane was the X-15A-2. It first flew on 28 June 1964, reaching 7,274 km/h (4,520 mph, or 2,021 m/s), thus establishing a new speed record. The fastest manned Jet-powered airplane is the SR-71 Blackbird, which reached the speed of, 3,529.56 km/h (2,193.17 mph). Note that we do not include space shuttles (which reach 28,000 km/h, or 17,500 mph during re-entry).
This joint program by NASA, the Air Force, the Navy, and North American operated the most remarkable of all the rocket research aircraft. Composed of an internal structure of titanium and a skin surface of a chrome-nickel alloy known as Inconel X, the X-15 had its first, unpowered glide flight on June 8, 1959, while the first powered flight took place on September 17, 1959. Because of the large fuel consumption of its rocket engine, the X-15 was air launched from a B-52 aircraft at about 45,000 ft and speeds upward of 500 mph. The airplane first set speed records in the Mach 4-6 range with Mach 4.43 on March 7, 1961; Mach 5.27 on June 23, 1961; Mach 6.04 on November 9, 1961; and Mach 6.7 on October 3, 1967. It also set an altitude record of 354,200 feet (67 miles) on August 22, 1963, and provided an enormous wealth of data on hypersonic air flow, aerodynamic heating, control and stability at hypersonic speeds, reaction controls for flight above the atmosphere, piloting techniques for reentry, human factors, and flight instrumentation. The highly successful program contributed to the development of the Mercury, Gemini, and Apollo piloted spaceflight programs as well as the Space Shuttle program. The program's final flight was performed on October 24, 1968.